Mannose-binding lectin and mannose-binding protein-associated serine protease 2 levels and infection in very-low-birth-weight infants
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چکیده
منابع مشابه
P 144: Sunflower Mannose binding Lectin-Associated Serine Protease Inhibitor-1 (SFMI-1) and -2: Significant Inhibitors of Mannose binding Lectin Pathway which Helps in Multiple Sclerosis Treatment
One of the important parts of innate immunity is complement system that occurs in three different ways; the classic, the alternative and the lectin pathway. The four pattern recognition molecules that have been identified till now are Mannose binding lectin (MBL), a component of lectin pathway, and three ficolins (ficolin1,-2 and -3) which compound to the carbohydrates of the cell surface. MBL ...
متن کاملThe association of mannose-binding lectin 2 polymorphisms with outcome in very low birth weight infants
OBJECTIVES Studies on the influence of mannose-binding lectin (MBL) deficiency on infection susceptibility in preterm infants have yielded controversial results. We investigated the association of genotype-based MBL levels with outcome in very-low-birth weight infants (VLBWI). METHODS We genotyped 3 genetic variants of MBL2 (rs1800450, rs1800451, rs5030737) in 6878 VLBWI. MBL plasma levels we...
متن کاملp 144: sunflower mannose binding lectin-associated serine protease inhibitor-1 (sfmi-1) and -2: significant inhibitors of mannose binding lectin pathway which helps in multiple sclerosis treatment
one of the important parts of innate immunity is complement system that occurs in three different ways; the classic, the alternative and the lectin pathway. the four pattern recognition molecules that have been identified till now are mannose binding lectin (mbl), a component of lectin pathway, and three ficolins (ficolin1,-2 and -3) which compound to the carbohydrates of the cell surface. mbl ...
متن کاملA true autoactivating enzyme. Structural insight into mannose-binding lectin-associated serine protease-2 activations.
Few reports have described in detail a true autoactivation process, where no extrinsic cleavage factors are required to initiate the autoactivation of a zymogen. Herein, we provide structural and mechanistic insight into the autoactivation of a multidomain serine protease: mannose-binding lectin-associated serine protease-2 (MASP-2), the first enzymatic component in the lectin pathway of comple...
متن کاملبررسی سطح سرمی C–Reactive Protein Mannoseو Mannose–Binding Lectin در افراد مبتلا به درماتوفیتوزیس
Background: Interleukin8 (IL-8) realized from keratinocytes in the presence of dermatophytic antigens causesinduction of acute responses in dermatophyte infection and subsequently production of acute phaseproteins occurs in hepatocytes. C–reactive protein (CRP) and Mannose–binding lectin (MBL) areacute phase proteins. Since few researches in the case of acute phase proteins in dermatophyticinfe...
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ژورنال
عنوان ژورنال: Pediatric Research
سال: 2018
ISSN: 0031-3998,1530-0447
DOI: 10.1038/s41390-018-0017-9